Case Report
The Beneficial Effect of Functional Electrical Stimulation of Miller Fisher syndrome (MFS) with Special Context to Guillain-Barré Syndrome Rehabilitation of a 25-year-Old Patient –A Systematic Review and Meta-Analysis
Borah AK1*, Goswami P2and Saikia H2
1Department of Neuro-Physiotherapy, Mahatma Gandhi University, District Ri Bhoi, Meghalaya, India
2Department of Physiotherapy and Orthopedic Rehabilitation, Sanjevani Hospital, Maligaon, Guwahati, Assam, India
2Department of Physiotherapy and Orthopedic Rehabilitation, Sanjevani Hospital, Maligaon, Guwahati, Assam, India
*Corresponding author:Arup Kumar Borah, Department of Neuro-Physiotherapy, Mahatma Gandhi University, District Ri Bhoi, Meghalaya, India. E-mail Id: barup614@gmail.com
Article Information:Submission: 14/04/2026; Accepted: 05/05/2026; Published: 07/05/2026
Copyright: © 2026 Borah AK, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Miller Fisher syndrome is a rare and atypical variation of Guillain-Barré syndrome, which includes the clinical trial of are flexia, ataxia, and ophthalmoplegia. Miller Fisher syndrome is commonly associated with the involvement of the lower cranial and facial nerves. Miller Fisher syndrome is one of the types of Guillain-Barré syndrome. Guillain-Barré syndrome has been defined to be the foremost incapacitating form of neurological disease following the disease polio. Guillain-Barré syndrome is a broad category that encompasses several types of acute immune-mediated polyneuropathies, the most common of which is acute inflammatory demyelinating polyradiculoneuropathy. It is considered part of the continuum of immune-mediated acute polyneuropathies, alongside GBS and Bickerstaff brainstem encephalitic (BBE). Charles Miller Fisher (1913-2012) first formally described this syndrome in 1956, and it has been recognized as a distinct clinical entity with in the GBS spectrum. We apply Functional Electrical Stimulation method of externally controlling muscles when signals from the brain can no longer control movement. This can happen after a spinal cord injury, stroke or neurological disorder such a multiple sclerosis. FES improves the quality of life (QoL) for patients with neurological disabilities across the globe. We also describe the patient’s clinical course,
diagnostic method, and therapy. The study demonstrates the value of early detection, quick action in treating Miller Fisher syndrome, and the possibility of full recovery with adequate therapy. Techniques utilized in physical therapy emphasize performing everyday tasks along with strengthening muscles. Miller fisher syndrome has a generally good prognosis, with most patients achieving full or near-full recovery within 8 to 12 weeks, and usually within 6 months.
Recovery involves the gradual reversal of ataxia (loss of balance), opthalmoplegia (eye movement issues), and arereflexia (lost reflexes). Early treatment with IVIg or plasmapheresis is key. In this paper we study a case report of a 25-year-old male patient who displayed the characteristic symptoms of Mill Fisher Syndrome. We also
investigate the patient’s clinical course, diagnostic method, and therapy. Hence, this case demonstrates the value of early detection, quick action in treating Miller Fisher syndrome, and the possibility of full recovery with adequate physiotherapy treatment. Techniques applied in physical therapy emphasize performing everyday tasks along with strengthening muscles.
Categories: Neurology; Pain Management; Physical Medicine and Rehabilitation.
Categories: Neurology; Pain Management; Physical Medicine and Rehabilitation.
Keywords:Miller fisher syndrome; Guillain-Barré syndrome; Physical recovery; Neurological recovery; Pain control
