Case Report
Pure Uterine Lipoma-A Review of Two Cases
Bhanji A1 and Neelakantan A2*
1Consultant Histopathologist, Plus Care Internationals Private Limited, Sewri, Mumbai, Maharashtra, India.
2Consultant Histopathologist & Laboratory Director, Plus Care Internationals Private Limited, Sewri, Mumbai, Maharashtra, India.
2Consultant Histopathologist & Laboratory Director, Plus Care Internationals Private Limited, Sewri, Mumbai, Maharashtra, India.
*Corresponding author:Amrita Neelakantan, Consultant Histopathologist & Laboratory Director, Plus Care Internationals Private Limited, Sewri, Mumbai-400015 Maharashtra, India. E-mail Id: amritaneel@yahoo.co.in
Article Information: Submission: 04/03/2024; Accepted: 17/04/2024; Published: 22/04/2024
Copyright:© 2024 Bhanji A, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Lipomatous uterine tumours are not commonly encountered, and pure uterine lipomas are a rare entity, as compared to their mixed counterpart lipoleiomyomas, with a low incidence of reported cases. [1] Their reported incidence is 0.03-0.2%. [2] Most reported cases have been of mixed type, consisting of admixture with smooth muscle or fibrous tissue. [3] Clinical diagnosis is rarely made, and the diagnosis is usually confirmed on pathological examination.
We report two cases, one of a 68-year-oldand one of a 55-year-old, both postmenopausal females, who presented with a bulky uterus diagnosed as fibroid uterus on ultrasonography. Upon hysterectomy, the specimens were sent for histopathological examination which revealed well circumscribed lesions in the myometrium composed of sheets and lobules of mature adipose tissue, with thin fibrous septae. The endometrium lining was pushed to the periphery. A diagnosis of uterine lipoma/lipomatosis was made.
The histogenesis of pure uterine lipomas are debatable, and a possible theory involves fatty metaplasia of smooth muscle cells of the myometrium. Awareness about this entity is important, as an accurate diagnosis can reduce the need for hysterectomy in these patients, owing to the benign nature of these lesions, and conservative management can be done.
We report two cases, one of a 68-year-oldand one of a 55-year-old, both postmenopausal females, who presented with a bulky uterus diagnosed as fibroid uterus on ultrasonography. Upon hysterectomy, the specimens were sent for histopathological examination which revealed well circumscribed lesions in the myometrium composed of sheets and lobules of mature adipose tissue, with thin fibrous septae. The endometrium lining was pushed to the periphery. A diagnosis of uterine lipoma/lipomatosis was made.
The histogenesis of pure uterine lipomas are debatable, and a possible theory involves fatty metaplasia of smooth muscle cells of the myometrium. Awareness about this entity is important, as an accurate diagnosis can reduce the need for hysterectomy in these patients, owing to the benign nature of these lesions, and conservative management can be done.
Keywords:Uterine Lipoma; Benign; Lipomatosis; Lipoleiomyoma