A two-year-old girl with refractory atopic dermatitis and multiple food allergies presented with elevated serum IgE (605 IU/mL). A six-week multidisciplinary intervention incorporating allergen elimination and nutritionally adequate dietary alternatives led to marked clinical improvement and reduction in IgE to 150 IU/mL. Most allergens could be reintroduced except milk. This case demonstrates that structured nutritional therapy, guided by a multidisciplinary team, can effectively manage pediatric atopic dermatitis associated with food allergies.