Case Report
Adenoma Malignum in Peutz Jegher Syndrome: Case Report
Riya Fathima1, Thara Pratap1, Pushpa Mahadevan2, Rashmi Unnikrishnan2, Dhanya Jacob1 and Muhammed Jasim Abdul Jalal3*
1Radiology, VPS Lakeshore Hospital, Kochi, India,
2Pathology, VPS Lakeshore Hospital, Kochi, India,
3Internal Medicine and Rheumatology, Olive Health Care, Thrissur, India
2Pathology, VPS Lakeshore Hospital, Kochi, India,
3Internal Medicine and Rheumatology, Olive Health Care, Thrissur, India
*Corresponding author:Muhammed Jasim Abdul Jalal, Department of Internal Medicine and Rheumatology, Olive Healthcare, Thrissur, Kerala, India Email: jasimabduljalal@yahoo.com
Copyright: ©2026 Fathima R, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Article Information:Submission: 18/12/2025; Accepted: 24/03/2026; Published: 28/03/2026
Abstract
Adenoma malignum, also known as gastric-type mucinous adenocarcinoma of the cervix, is a rare variant of mucinous adenocarcinoma, previously referred to as minimal deviation adenocarcinoma. It accounts for approximately 1–3% of all cervical adenocarcinomas. Adenoma malignum is often associated
with Peutz-Jeghers syndrome and mucinous tumors of the ovary. This case is unique due to its prolonged indolent clinical course, with no evidence of local invasion or metastasis over a period of six years, underscoring the deceptively benign clinical, radiological, and pathological appearance of this malignancy.
We emphasize the subtle diagnostic clues that can facilitate early recognition of this rare but aggressive entity.
Keywords:Adenoma malignum; Cervical cancer; Peutz–Jeghers syndrome
