Obesity is one of the leading causes of chronic inflammatory disorders like type 2 diabetes, cancer, cardiovascular diseases and neurodegenerative diseases. This is also affecting the health care system by increasing health care costs. This is becoming a burden on both developing and developed nations equally. Weight reduction helps to reduce this burden. A reduction in 1kg body weight reduces the risk of getting diabetes by 16%. Grains occupy the major portion of meal plate, replacing refined grains with whole grains like millets helps to reduce weight as well as improve the nutrient content of food. Millets are ancient foods grains rich in micro minerals, flavonoids, phenolic acids. These millets are weed varieties that can be easily grown in varied climatic zones. They are economical and easily available. Promoting millets to replace refined grains like enriched wheat flour, white rice helps to promote weight loss as well as reduce micronutrient deficiencies.